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3g,h and Extended Data Fig

Role of sirtuins in physiology and diseases of the central nervous system

Maintain mineral balance: Because long-term glutathione use may reduce zinc, ensuring diet rich in zinc (nuts, seeds, lean meat, legumes) is wise

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The real goal is helping patients regain control over appetite and develop sustainable habits

Key considerations often include: Individual biological context, such as sleep patterns and circadian stability Overall stress exposure and recovery capacity General metabolic and inflammatory status The intended purpose of use within a broader longevity strategy For this reason, Epitalon is commonly applied in defined cycles with clear boundaries, rather than as a long-term or indefinite therapy