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Your body uses peptides as signaling molecules for biological pathways and as hormones

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Keywords Carbon monoxide (CO) Source: a colorless, odorless gas produced by incomplete combustion of organic compounds most fatalities result from fires, stoves, portable heaters, however automobile exhaust cause approximately one third of deaths (these often are associated with malfunctioning or obstructed exhaust systems and suicide attempts) cigarette smoke is a significant source of CO natural gas contains no CO, but improperly vented gas water heaters, furnaces, kerosene space heaters, charcoal grills, hibachis, and Sterno stoves all emit CO Mechanism of Action: CO toxicity causes impaired oxygen delivery and utilization at the cellular level CO affects several different sites within the body but has its most profound impact on the organs with the highest oxygen requirement (eg, brain, heart)

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Oxidative stress can further cause oxidative damage to nucleic acids, proteins, and lipids, subsequently resulting in local melanocyte damage, apoptosis, and induction of an autoimmune response to attack more melanocytes, which causes progressive skin pigment loss 9

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