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However, an important drawback is that the results of studies performed in small animals are of limited applicability to human beings due to their varying size and anatomy of the liver and their faster metabolism [17]

Chapple IL, Brock GR, Milward MR, Ling N, Matthews JB

Microfilaments, the thinnest of these filaments, are involved in cell morphology and motility and consist of actin filaments (F-actin) that are polymerized from monomeric globular actin (G-actin)

Suicide risk is high due to poor quality of life, with one example of a patient completely bed-bound for years who felt isolated, struggled with severe exhaustion and pain, often unable to speak or have the cognitive energy to focus, consequently deciding to end her life [19]