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Description

10 As G6PD is X-linked, heterozygous females can carry severe mutations and remain symptomless, whereas hemizygous males with Class I mutations suffer from chronic nonspherocytic hemolytic anemia (CNSHA)

Moreover, an antibodydrug conjugate combining the anti-CD26 monoclonal antibody YS110 with triptolide (Y-TR1) selectively targets CD26-positive cancer cells (malignant mesothelioma and leukemia), effectively inhibiting RNA polymerase II activity [1027]