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Duman RS

Sphingosine-1-phosphate (S1P), by inhibiting MMPs and promoting glycocalyx synthesis, has shown protective effects in preclinical models

[DOI] [PubMed] [Google Scholar] 16.Sun G.W., Chen Y., Liu Y., Tan G.Y., Ong C., Tan P., Gan Y.H

"The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations"

1996;40:C851C862

In contrast, erastin failed to induce ferroptosis in our in vitro model, potentially because, as previously published, CLL cells are inherently limited in their ability to take up cystine under baseline conditions (Supplementary Fig