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Loss of PMK-1 (transcription factor of p38 MAPK) compromises the extended lifespan of daf-2(e1370) (insulin/insulin-like growth factor (IGF) receptor longevity mutant) 45

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Key Areas of Research: Structural: Collagen, matrix, tendon Vascular: Angiogenesis, nitric oxide, repair Dermatological: Wound closure, vessel growth, cells Systemic: Protection, viability, recovery Together, these findings suggest broad experimental utility for BPC-157 across multiple biological pathways

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