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In accordance with the elevated hepatic GSSG/GSH ratio in HFD-fed mice, HFD consumption markedly increased hepatic 4-hydroxynonenal formation (Fig

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Figure 1 below presents a classification of the antioxidants with examples

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This is proceeded by peptide bond formation between -Glu-Cys and the amino acid glycine which results in a reduced form of glutathione, known as GSH (Pophaly et al

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Nikseresht S, Khodagholi F, Ahmadiani A (2019) Protective effects of ex-527 on cerebral ischemia-reperfusion injury through necroptosis signaling pathway attenuation

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Notable limitations include non-specificity: numerous non-phenolic reducing agents (e.g., ascorbic acid, proteins, reducing sugars, and certain inorganic ions) react, leading to overestimation of TPC

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Chem Biol Interact 160(1):140

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