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At low concentrations of Asc (less than 20 mmol/L), chloroplast APX activity is rapidly decreased in the presence of H 2 O 2 , with an inactivation half-life of the 30 s

IGF-1 can regulate the proliferation and differentiation of muscle satellite cells by activating PI3K/Akt (77, 129, 130) and promote collagen formation, in turn promoting skeletal muscle hypertrophy (131)

They can be effective supplements alongside diet and exercise programs

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Treadmill and wheel exercise protect against JNK/NF-B induced inflammation in experimental models of knee osteoarthritis

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