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This reversibility and the fact that the reaction does plateau and approach equilibrium will be taken into account within the kinetic model by including maxima and minima in the functions (see below)

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Since the GT Plus assay is designed to identify HCV subtypes 1a and 1b as well as genotype 6, three main reasons may be pivotal if the GT Plus assay provides a not detected result for genotype 1 samples without subtype by the GT II assay

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