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It has well-documented anti-inflammatory properties and has been studied for its role in protecting against age-related eye disease

Rosas-Ballina M, Ochani M, Parrish WR, Ochani K, Harris YT, Huston JM, Chavan S, Tracey KJ

Diabetologia 60 , 16391647 (2017)

2 DCFDA and C11-BODIPY, respectively ( 2+ , Mn 2+ , Ni 2+ , Co 2+ ), potentiated erastin-induced death ( Because two erastin targets, VDAC2 and VDAC3, reside in the mitochondria, it was hypothesized that erastin-induced death involved aberrant ROS production by the mitochondrial electron transport chain (ETC)

doi: 10.1038/s41589-022-01017-3 92 SharabiATsokosGC