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Specifications: Form: Lyophilised powder Unit Size: 10 mg Appearance: White to off-white solid Storage (unreconstituted): -20 C, dark, dry Reconstitution: Sterile bacteriostatic water Stability (reconstituted): Store at 28 C, short-term Usage Notice: For research use only

In the Phase 2 Lancet trial, orforglipron 45 mg reduced HbA1c by up to 2.1 percentage points at 26 weeks, exceeding the reduction achieved by dulaglutide 1.5 mg (the active comparator)

It is less preferred but used when there is less chance of absorption through skin

FDA-approved for diabetes

Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

NNMT slows down fat cell metabolism (which makes losing weight even more difficult.) By blocking NNMT, 5 Amino 1MQ can prevent this metabolism slow-down and promote weight loss