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S.Ferrer-SuetaG.et al (2020)

Reaction 3: 6-Phosphogluconate + NADP Ribulose-5-Phosphate + CO + NADPH + H The second reaction involves the oxidation of 6-phosphogluconate, which results in the production of NADPH, carbon dioxide (CO), and ribulose-5-phosphate

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Therefore, the suggested mechanistic model may consist of two consecutive phases: (i) the transferring of selenium between selenol (R-Se-H) and selenenic acid (R-SeO-H) followed by (ii) the transferring of selenenic acid (R-SeO-H) to seleninic acid (R-SeOO-H) although this has not been experimentally verified

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Cell 138:286299 Jan M et al (2011) Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker