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Ecotoxicology 12 , 183197 (2003)

While liquid formulations allow for the uniform distribution of vaccine components, they have certain limitations, such as a short residence time in the nasal cavity, low stability, and the need for a cold chain distribution system (Scherlie 2020)

Despite the rapid ET accumulation in liver, lung, small intestine (jejunum/ileum) and the colon, it appears that these tissues became saturated after repetitive doses for one week, with no further increase in ET with administration up to 28 days

Often, this means storing them in their original containers in a cool, dry place out of direct sunlight

El cartlago hialino es un tejido resistente y elstico formado por condrocitos, que son las clulas encargadas de producir la matriz extracelular (MEC), compuesta mayoritariamente por colgeno tipo II y proteoglucanos (PGs)

J Biol Chem, 2012