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[,] OCD behaviour has been linked to hyperactivity in the orbitofrontal cortex, anterior cingulate and ventromedial striatum

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doi: 10.1016/j.isci.2021.102849 [DOI] [PMC free article] [PubMed] [Google Scholar] 522

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Observations of hyperactive disorganized motility, commonly made by manometric recording methods in vivo, reinforce the evidence that a subset of the pool of inhibitory musculomotor neurons is tonically active and that drug-induced blockade or ablation of these neurons releases the circular muscle from the inhibitory influence [3436]