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(5) Identification of the Rebate Period CPI-U As specified in section 1847A(i)(3)(F) of the Act, at 427.302(f), we proposed to codify the policy described in section 50.6 of the revised Medicare Part B Drug Inflation Rebate Guidance, that the rebate period CPI-U means the greater of the benchmark period CPI-U index level and the CPI-U index level for the first month of the calendar quarter that is 2 calendar quarters prior to the applicable calendar quarter in which the Part B rebatable drug is furnished

Furthermore, in the presence of two well-known inflammatory cytokines, the treatment of chondrocytes with palmitate resulted in a further decrease in cell viability compared to the inflammatory cytokines alone (Fig

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This gives it a builtin targeting mechanism for gutfocused research and makes oral delivery particularly relevant in colitis models

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