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For example, colitis may develop into colon cancer after inflammatory infiltration, increased production of ROS, impairment of antioxidant defenses, DNA damage, and genetic and epigenetic alterations, resulting in the transformation of epithelial cells [234]

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RSSP in plasma Plasma content of RSSP is very different from the intracellular one both in terms of concentration and species of LMM-SH bound to proteins

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