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Animal experiment All procedures for animal experiments in this study were authorized by the Institutional Animal Care and Use Committee (IACUC) of Seoul National University (Approval Number: 220038-S1A0) and complied with the guidelines for the care and use of laboratory animals

This change results in a missense change, an alanine to valine substitution, at codon 222

It often resolves spontaneously but can sometimes prolong hospital stays and increase patient discomfort

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