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There is a significant body of research, mostly from the 2000s, on the homocysteine-lowering benefits of B12 in patients with end-stage renal disease and who are on haemodialysis (HD), 80100% of whom have elevated homocysteine levels

Brisby, H

Collectively, these findings indicate that carefully engineered CQDs offer low in vitro toxicity while offering broad functional potential in biomedical research and applications

It can lead to raised levels of a substance called homocysteine, which can increase the risk of heart disease and stroke

It is involved in tissue-building and repair and detoxing our bodies