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82203014, 81972863, 82030082, and 22307068), the Radiation Oncology Innovate Unit, Chinese Academy of Medical Sciences (Grant No

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In the present study, the significant reductions of liver and plasma GSH (Table 3) and cystathionine concentrations (Table 2), in addition to the significant correlation between these two compounds, suggested that modulation of the methyl balance and the consequent reduction of Hcy can down-regulate the trans-sulfuration pathway in a dose-dependent response