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Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, et al

Cell viability (using MTT assay), cell apoptosis (via flow cytometry), the level of malondialdehyde (MDA), and the expression levels of hsa-miR-16-5p, hsa-miR- 34a-5p, B-cell lymphoma 2 (BCL-2), cyclin D1 (CCND1), and sirtuin 1 (SIRT1) were measured (via real-time PCR)

Studies in a humanized APOE3-Ch knock-in mouse model, crossed with an A plaque-depositing model, demonstrated that ApoE3-Ch alters microglial responses and suppresses A -induced tau seeding and spreading (Chen et al., 2024)

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