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If the cause of the pain is not immediately clear, imaging studies may be ordered

Decreased motility of the lower esophageal sphincter in a rat model of gastroesophageal reflux disease may be mediated by reductions of serotonin and acetylcholine signaling

doi:10.1097/MAO.0000000000002564

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So far, most BPC-157 studies including early research have been done in animal models giving investigators solid proof of how the peptide works and how it can be used in the lab