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Sudden growth over days to weeks, or a lump that continues to expand over months, should prompt evaluation

LPS can cross the gut barrier, especially when the barrier becomes leaky due to inflammation, and enter the bloodstream, triggering systemic inflammation

Dose-dependent histopathological findings in the dogs administered LAVERDIA included lesions in the testes and epididymides (moderate to marked seminiferous tubules degeneration/atrophy, minimal to moderate vacuolation, and minimal Leydig cell hypertrophy in the testes

In a 2024 preclinical study, Feng et al

Luz-Crawford et al., 2016

It stimulates dermal papilla cell proliferation and protects these cells from noxious stimuli including dihydrotestosterone (DHT)-induced stress, the primary driver of androgenic alopecia