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Results may be reported as wild type, heterozygous, homozygous, or compound heterozygous

Over the past few decades, there has been a growing interest in understanding the neurobiological underpinnings of glutamatergic dysfunctions in the pathogenesis of depressive disorders and the development of new pharmacological and non-pharmacological treatment options

Statistical methods All statistical analyses were performed, and all data figures were created using PRISM GraphPad version 9.1.2 (La Jolla, USA) unless otherwise specified

74 PLC1 catalyzes the synthesis of diester glycerol and inositol (1,4,5)-trisphosphate as second messengers that trigger mitogen-activated protein kinase, protein kinase C (PKC) and calmodulin phosphatase

VIC can also destabilize amyloid fibers, thus being a protective factor against fiber cytotoxicity