glutathione in ovarian cancer a double-edged sword

glutathione in ovarian cancer a double-edged sword Redox-Regulated Iron Metabolism and Ferroptosis Cancer: Molecular Insights and Therapeutic Opportunities Ferritinophagy as a Double-Edged Sword

Name: glutathione in ovarian cancer a double-edged sword Redox-Regulated Iron Metabolism and Ferroptosis Cancer: Molecular Insights and Therapeutic Opportunities Ferritinophagy as a Double-Edged Sword
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SKU: 24149480905
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Ferritinophagy as a Double Edged Sword in Cancer: Novel Insights into Therapeutic Targeting of Iron Driven Ferroptosis Cell Biochemistry and Biophysics Springer Nature Link N Acetyl Cysteine as a promising therapeutic approach in ovarian cancer: potential and perspectives PMC Frontiers The double edged sword role of hydrogen sulfide in hepatocellular carcinoma Role of SLC7A11 xCT in Ovarian Cancer Lipocalin 2: a double edged sword in cellular ferroptosis Cell Biology and Toxicology Springer Nature Link Ferroptosis in ovarian cancer: Regulation, immunity, and therapeutic potential with the tumor microenvironment ScienceDirect

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This is as a result of lifestyle and health concerns evolving as one ages

doi: 10.1021/acs.jmedchem.5b01641 58 HongS

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Recent studies have shown that IFN- can downregulate SLC3A2 and SLC7A11 while upregulating ACSL4, promoting tumor cell ferroptosis

Previous research has shown that GPx1 is an effective antioxidant enzyme that cannot be replaced by any other selenoprotein to protect against generalized oxidative stress [74,75,76]

It is well known that thiols, such as the tripeptide glutathione (GSH), are highly efficient antioxidants in living cells and work by reacting with reactive oxygen species through both non-radical and radical reactions (8)