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Furthermore, oxidative stress and free radical production are increased because astrocytes, which maintain the integrity of the bloodbrain barrier, are targets of oxidative damage (Carvajal-Flores et al

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Since an exogenous antioxidant exhibits anticancer effect by both antioxidant (chemopreventive) and prooxidant (chemotherapeutic) mechanisms, the dose is a critical factor

Antitumor Efficacy and Amelioration of Oxidative Stress byTrichosanthes Dioicaroot against Ehrlich Ascites Carcinoma in Mice