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Basilea originally partnered with Johnson & Johnson to develop the molecule in 2005 but ran into a series of regulatory challenges

10.1016/j.survophthal.2019.01.011 13 CudeiroJ.RivadullaC., and (1999)

Isolation of live Borrelia burgdorferi sensu lato spirochetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis

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early intervention halts this progression Reduced frequency of future attacks urate lowering therapy is essential for long term management of gout, lowering the risk of flares from several per year to near zero in many patients Accurate diagnosis conditions like septic arthritis can mimic gout symptoms