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Brugre J-F, Borrel G, Gaci N, Tottey W, Otoole PW, Malpuech-Brugre C

One study on diabetic rats found that ipamorelin stimulates insulin release through adrenergic receptor pathways and calcium channels [6]

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However, the large-scale production, long-term storage stability, potential cytotoxicity (such as size-dependent oxidative stress), and clinical safety of nanoformulations still need to be further optimized