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From the chemical aspect, the biphasic property of CAP can be well harnessed by antioxidants or their counteractive inhibitors for buffered effects and constrained therapeutic window (Fig

Another survey conducted to understand the prevalence of needle phobia in adults concluded that 63.2% of adults experienced some degree of needle phobia

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These compounds may enhance phagocytosis by modulating intracellular reactive oxygen species (ROS) at sub-toxic concentrations, where ROS act as secondary signaling molecules that facilitate cytoskeletal rearrangement and promote phagosome formation

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Ultimately, the model enhanced our understanding of the pathogenesis and treatment of immune reactivity against self, or as Paul Ehrlich himself called it, horror autotoxicus ( rubor (redness), tumour (swelling), calor (heat), and dolor (pain) (Figure 3)