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Stress: Chronic stress floods the body with cortisol, which can interfere with memory and cognitive function when levels remain elevated

This storage capacity means your body can draw on reserves when dietary intake is temporarily low

Beyond these findings regarding Glu and GABA, cumulative evidence has indicated dysfunction of the Gln-Glu cycle and the excitatory versus inhibitory balance (E/I balance)

This activity is mediated by the vitamin D nuclear receptor (VDR), a DNA-binding protein that interacts directly with regulatory sequences near the target genes

A role of the enzyme in modulating stress responses by controlling JNK activity was also proposed 56, 57

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