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Image: Michail_Petrov-96/Thinkstock Vitamin B12 may not be high on your nutritional radar, yet it is essential to some of the body's most important functions, like forming red blood cells and maintaining nerve function

Furthermore, the long-term safety of brodalumab remains to be determined in the phase three study

Two subjects in the fasting group withdrew from the trial at the end of the first cycle during the washout period and the fourth cycle, one subject experienced an adverse event (AE) on the second day of dosing in the second cycle, and the investigator judged that withdrawal from the study would be in the best interest of the subject to withdraw from the trial

doi: 10.1016/S0140-6736(15)01223-4 [DOI] [PubMed] [Google Scholar] 38

Nausea: Particularly with oral administration

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