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Not getting enough B12 is very common in humans and it's not only due to lack of intake, but can also be from improper absorption from your body

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Effect of age at the start of iron chelation therapy on gonadal function in beta-thalassemia major

You may notice: Dark patches around the cheeks, hands, or knuckles Diffuse pigmentation that looks like uneven skin tone or melasma Research has linked B12 deficiency to melanin overproduction , particularly in darker skin tones

Once opened, vials remain microbiologically stable for up to 28 days when stored appropriately