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Finally, the anhedonia phenotype of CD2-KO mice was selectively rescued by NAC pre-treatment

Oxidative stress is also important for HDAC4 as there are substantial evidences supporting that elevation of ROS production results in the increase of nuclear localization of HDAC4

Improper storage is like buying a high-performance engine and filling it with sugar

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

Because bortezomib is hypothesized to induce painful neuropathy through a mitochondrial stress mechanism (73, 74), the sEHI may also improve outcomes in combination with this therapy as well

Building upon these findings, we systematically evaluated the protein degradation efficacy of Psa-AR versus conventional P-AR