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Shilajit attenuates behavioral symptoms of chronic fatigue syndrome by modulating the hypothalamicpituitaryadrenal axis and mitochondrial bioenergetics in rats

Moreover, clinical trials employing adipose stem cell-derived EVs in dermatological applications reported mild side effects such as transient erythema but no serious adverse events, indicating favorable safety profiles in humans [145]

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Supplementary Figure 4 ATAC-seq, ChIP-seq, and RNA-seq read density profiles at the NADK, NADK2, G6PD, PGLS, PGD , and TALDO1 loci

Collectively, these perspectives aim to provide a timely, CRC-specific, and mechanism-based framework for developing clinically actionable strategies targeting mitochondrial metabolism