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The mechanisms underlying this age-related NAD+ depletion involve multiple factors, including increased consumption by DNA repair enzymes, reduced biosynthesis, and enhanced degradation by CD38 and other NAD+-consuming enzymes

[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Tolkien Z., Stecher L., Mander A.P., Pereira D.I., Powell J.J

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