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and (4) MCAO group treated with the optimized FIN nano-embedded dry powder (1 mg/kg of FIN) reconstituted in 0.9% saline solution (~ 15 L) intranasally (IN) (MCAO + IN FIN group)

Inflammatory cytokine dysregulation and chronic inflammation in ME/CFS Current evidence suggests that chronic low-grade inflammation, mediated by an imbalance between pro- and anti-inflammatory cytokines, is a pivotal mechanism in ME/CFS