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doi:10.1080/01635581.2015.976315 Isherwood J, Arshad A, Chung WY, et al

compsn according to claim 9 is characterized in that, said pharmaceutically acceptable carrier is 1500 part

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In HFD-fed mice, AT-SIRT3OE mitigated the secretion of inflammatory cytokines and chemokines from eWAT, thereby improving systemic inflammation and insulin sensitivity

On the other hand, in MDA-MB-231 cell line, telaglenastat monotherapy by itself showed a profound effect on proliferation, migration, and invasion of the cells, with dox-induced ELAVL1 silencing marginally contributing with a further effect when performed in combination, especially for the migration of the cells (Supplementary Fig