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& Crommelin, D
Challenging rats with MTX evoked hepatotoxicity as manifested by elevated liver function enzymes in serum and disarrayed hepatic histopathologic features, which aligns with previous reports (Karabulut et al., 2020
When mitochondria function well, they generate fewer reactive byproducts, which may reduce overall oxidative burden and support glutathione in its active, protective form
Obesity Reviews , 21 , e13053
These allosteric effects can be modulated through the action of carnitine acetyltransferase (CAT), a mitochondrial isoenzyme that transfers the acetyl groups from acetyl-CoA to carnitine, forming acetylcarnitine