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S2CID 23877884

All patients received either PD-1 monotherapy (nivolumab/pembrolizumab) or a combination of nivolumab and ipilimumab

Interestingly, we found increased interstitial fibrosis and vascular abnormalities consistent with inflammation and fibrosis in coronary and aortic sections from older GPx1 +/ mice [39], illustrating the detrimental effects of chronic oxidative stress on the vasculature

Instead of wasting money, time and effort in developing newer agents that suffer the same resistance problem, focus should be directed toward tackling the already existing drug resistance

Trigger factor and DnaK possess overlapping substrate pools and binding specificities

doi: 10.1093/ajcn/85.5.1275 53 ResseguieMSongJNiculescuMDda CostaKARandallTAZeiselSH