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Bilirubin Heme oxygenase-1 (HO-1) is the enzyme that generates carbon monoxide, iron, and biliverdin using the heme fraction as a substrate [39], and biliverdin reductase that reduces biliverdin to bilirubin being this molecule the ending product of the heme degradation

Berin, M

It plays a crucial role in maintaining the homeostatic balance of cells and organisms

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