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The main toxicity provoked is acute liver damage, which is mechanistically provoked by the aberrant adduction of the toxic metabolite N-acetyl p-benzoquinone imine (NAPQI) to cysteinyl residues of key liver proteins [105]

Isolation of peripheral blood mononuclear cells (PBMCs) and single-cell suspensions was performed using Ficoll Paque Plus (Millipore Sigma) density gradient centrifugation

For females, GPx helps maintain ovarian function by balancing reactive oxygen species essential for ovulation but harmful in excess

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The herb kava has caused a number of cases of idiosyncratic liver injury, ranging everywhere from asymptomatic to fatal

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