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2.2 Pathogenesis and pathophysiology of hyperuricemia Hyperuricemia is the precursor state to gout, but its pathophysiological impact extends far beyond the joints, involving multiple systems, including cardiovascular diseases, chronic kidney disease, and metabolic disorders (Wang Q

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In addition to that, a meta-analysis report reveals that lead exposure is associated with lower semen volume, decreased sperm count and vitality (66)

Greene, C., Hanley, N

May 2022;38(5):379-384