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Thus, a direct correlation between O -GlcNAc and cell nutrient composition exist, allowing O -GlcNAc to correlate with many pathologic phenotypes associated with various diseases including DR

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Mitapivat significantly reduced the amount of band 3 and membrane associated peroxiredoxin-2 (Figure 3D) in the released vesicles, which constitute the protein machinery involved in generation of erythroid vesicles (36, 37)

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Secondly, accurately detecting nROS currently poses significant challenges owing to the difficulties associated with fluorescent probes crossing the nuclear membrane and avoiding DNA damage response (DDR) pathways

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The double-tagged mRFP-eGFP-LC3B plasmid was utilized to monitor altered autophagolysosomes

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