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Zhao S, Consoli U, Arceci R, Pfeifer J, Dalton WS, Andreeff M

100 mg Polyphenols (95%)

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De novo PrfA* (G145S) allele introduction was performed by amplifying the PrfA* allele and flanking regions and assembling into pLIM [25]

10.1002/14651858.CD011626.pub2 152

However, in some MG patients, reduced AIRE expression or loss-of-function mutations compromise this mechanism, allowing autoreactive T cells to escape thymic deletion (32)