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However, overexpression of PGC-1 reduces autophagy marker levels, improves mitochondrial metabolic function and antioxidant capacity, thereby alleviating muscle atrophy, offering a potential approach to age-related sarcopenia (80)

Dysregulation of this pathway is a contributing factor to insulin resistance and associated metabolic diseases (30, 34, 35), including Type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), dyslipidemia, and obesity-related complications

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If you find yourself struggling to keep up with the demands of daily life, low energy levels may be holding you back