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10.1038/nature12820 20

doi: 10.1038/s41579-022-00713-0 6 Blanco-MeloDNilsson-PayantBELiuWCUhlSHoaglandDMllerRet al

7 , e1016 (2018)

Dosing Protocol Suggested daily titration approach based on clinical trial protocols [4] [5]

Additionally, hyperglycemia can lead to histological alterations in the epididymal duct, including decreased germ cell populations, reduced stereocilia, clustering of epithelial cells, lipid vacuolization, and inflammation ( Reduced sperm quality is a recognized issue in diabetes, particularly in cases of T1DM