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Acknowledgements The authors have no funding sources to declare

Stress: One common trigger for IC symptoms is stress

Improvement of hepatic fibrosis and patient-reported outcomes in non-alcoholic steatohepatitis treated with selonsertib

Chronic Illness : Conditions such as diabetes, liver disease, and neurodegenerative disorders can lower levels

We further confirmed the chondrogenic and regenerative capacities of MSCs isolated using FreSHtracer in vitro and in vivo

93 LEP enhances IL-1-induced production of MMP-1, MMP-3, and MMP-13 in human OA cartilage, 94 indicating its role as a catabolic regulator of cartilage metabolism