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doi:10.1515/jbcpp-2020-0099

Additional studies have shown that the upregulation of sirtuin3 (SIRT3) promotes the AMPK-mTOR pathway and reduces GPX4 level to enhance autophagy activation, leading to ferroptosis in trophoblast cells (Li et al., 2020)

Pharmacologically targeting FSP1 induces ferroptosis in various cancers, synergizing effectively with GPX4 inhibitors ( In this pathway, CoQ10 is crucial, and the inhibition of its synthesis leads to increased LPO (Mao et al., 2021)

Pretreatment with GSHee blunted the effects of the subsequent injection of fentanyl in a manner that suggest that the actions are heavily dependent on the actions of fentanyl itself on some parameters but not others

No change in mTORC1 signaling or phosphorylation of eIF2 was observed with ATF4 knockdown in this setting (Figure 4Afigure supplement 4A)

Notably, this mutation did not affect the interaction between STK38 and RIPK1 (Fig