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Low temperatures often lead to an energy overflow where carbon fixed during brief favorable periods cannot be fully utilized for growth, thereby being redirected into the phenylpropanoid pathway and other carbon-rich secondary metabolites (Jaakola and Hohtola, 2010)

Studies indicate that nilotinib exhibits favorable safety and tolerability, degrades -syn, prevents parkin inactivation, and inhibits c-Abl, thereby potentially mitigating neurodegeneration [158, 159]