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In rare cases, it may cause stomach pain, stomach upset, diarrhoea, nausea, and vomiting

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Low thyroid levels are particularly common among women over 60 years of age

In addition, a trend toward delayed progression to kidney failure and the need for dialysis was observed in the probiotic group compared with the placebo group at a 3-year follow-up

Moreover, the increased relative abundance of Succinivibrionaceae (associated with starch degradation) in the rumen was also probably related to the higher production of propionate (Iqbal et al., 2018) whereas the decreased proportion of bacteria Desulfobulbus (involved in propionate degradation) may have also contributed to increasing the proportion of this SCFA (Kremer and Hansen, 1988)