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One review that included nine studies of collagen supplementation in dogs with osteoarthritis found collagen was unable to improve objective measures of joint mobility or subjective measures of pain

These mean the native peptide therapy, and the myotendinous junction recovery along with the described beneficial effect in the muscle [21,35,36,37] and tendon healing [18,19,20,22], unmistakably attributed all of its effects (i.e., functional, biomechanical, macroscopic, and microscopic effects and exemplified mechanism(s)) to define myotendinous junction healing in practice

Clin Invest Med 1994;17:244-52

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Over-40 and over-50 multivitamins: "These formulations typically include higher levels of bone-supporting nutrients, like calcium, magnesium and vitamin D

doi: 10.1146/annurev-nutr-071715-050947